Developments in Inhalational Devices: Consequences for the Treatment of Chronic Obstructive Pulmonary Disease

  • Vibhu Pandey
  • Jameel Ahmad

Abstract

Background: Inhaled therapies are essential for managing symptoms and preventing exacerbations of Chronic Obstructive Pulmonary Disease (COPD), a cause of morbidity and mortality that is prevalent throughout the world. In order to enhance patient outcomes, innovative inhaler designs have been developed in response to limitations in classic inhaler technologies, such as inadequate drug delivery and poor adherence. Objective: This review focuses on advancements in smart inhalers, particle engineering, and usability enhancements, aiming to explore recent breakthroughs in inhaler technology and their potential impact on the management of COPD. Methods: A thorough literature review was performed to locate peer-reviewed studies, clinical trials, and reviews published in the last ten years. Focus was directed towards technologies that improve drug delivery, adherence monitoring, and patient usability. Outcomes: Innovative technologies, like smart inhalers, incorporate digital feedback and adherence monitoring, facilitating personalized treatment. Innovations in device design, such as soft mist inhalers and advanced dry powder inhalers, improve drug deposition efficiency and tackle patient-specific issues, including diminished inspiratory effort in elderly individuals. Enhanced usability features, such as optimized dose actuation mechanisms, have shown promise in improving adherence and minimizing errors. Summary: Advancements in inhaler technology offer transformative potential in COPD management, aligning with trends toward personalized and patient-centred care. By addressing barriers to effective therapy, these innovations improve drug delivery, enhance adherence, and reduce exacerbation rates. Further research is needed to integrate these technologies into routine clinical practice and assess their long-term impact on patient outcomes.

Published
2025-01-16
Section
REVIEW ARTICLES