A Study on Side Effect of Antiretroviral Therapy Among People living with HIV/AIDS

  • Yasir Alvi Senior Resident, Dept. of Community Medicine, JN Medical College, AMU, Aligarh, India
  • Najam Khalique Professor, Dept. of Community Medicine, JN Medical College, AMU, Aligarh, India
  • Anees Ahmad Professor, Dept. of Community Medicine, JN Medical College, AMU, Aligarh, India
  • Shamaila Sameen Junior Resident, Dept. of Pathology, JN Medical College, AMU, Aligarh, India
Keywords: Adverse drug reaction, HIV/AIDS, PLHA, Side effects, ART

Abstract

Background: With antiretroviral therapy being the only tool against HIV/AIDS in patients suffering from the disease, research would be beneficial in identifying the side effects from ART. Thus, we conducted this study to estimate the prevalence of side effects and to find out its associated factors among people living with HIV/AIDS.

Methods: A cross-sectional study was conducted at the ART centre, Aligarh. A total of 434 people living with HIV/AIDS were approached with study tools comprising of pre- structured proforma. The current and lifetime prevalence of side effects were estimated. Data was entered in MS Excel and presented as pie chart and bar diagram.

Results: We found the self-reported prevalence of side effects in HIV positive patients to be 18.7 (81/434) at the time of interview and 91.7% (398/434) in lifetime since the start of ART. Most of the PLHA had dizziness (65.4%) while abdomen pain and nausea/vomiting were reported by 28.4% and 27.2% respectively. The side effect was found to be common among younger age group, females, lower socio-economic class and patients who were recently started on treatment. The patients taking tenofovir and efavirenz combination therapy were also found to have more side effects.

Conclusion: This study found the prevalence of ever having side effect to ART to be about cent percent while it is still considerably high in the last 30 days. A proper action and further researches are required to explore and manage side effects associated with ART.

Published
2019-06-30