Safety study of Baobarang (Embelia ribes Burm. f.)
Background: Herbal Unani drugs represent an important class of traditional medicine system. According to WHO nearly 70-80% of world population relies on traditional medicines. Herbs are used for the treatment and prevention of various ailments. With increasing interest in herbal products there is an increasing concern over the herbal drugs safety. People assume that they are natural so they are safe but there are incidences of toxicity and adverse effects. Safety study of herbal drugs and food items is now mandatory as per WHO guidelines, to prevent the toxicity due to the material found in the soil and the environment.
Methods: Plants are vulnerable to be contaminated with harmful ingredients. It includes determination of Microbial load, Heavy metals by AAS, Aflatoxins LC-MS/MS and Pesticide Residues using GC-MS/MS. Therefore, the present study aimed to evaluate safety parameters in Baobarang (EmbeliaribesBurm. f.) belonging to the family Myrsinaceae.
Results: Safety study revealed the presence of heavy metals, lead, cadmium, mercury and arsenic within permissible limit as per WHO guide line while aflatoxin, pesticides and microbial load were found to be absent in the crude drug sample.
Conclusion: From the safety profile obtained it can be concluded that the test drug is safe for use and free from chances of toxicity
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