Fluconazole Induced Fixed Drug Eruption: A Case Report

Abstract

Fluconazole is most commonly used drug in treatment of dermatophytes infection. Fluconazole induced FDE is one of the rare adverse drug reactions reported in literature. We report a case of 25-year-old male patient attended in dermatology OPD with lesions over the skin, round in shape. He was diagnosed as a case of tenia corporis and was prescribed Fluconazole 150 mg once in a week. He took drug at 2 p.m. and after 3 hours he noticed multiple well-defined hyperpigmented patches measuring 2-3 cm in diameter over left forearm and upper back area. He told that he had experienced same type of patches on same spot with same features 2 times in past. On the basis of history and examination, he was diagnosed as a case of fixed drug eruption associated with fluconazole. On both sites hyperpigmented patches were improved on 8th day after discontinuation of fluconazole.